Project Title WarCalc: Warfarin Dosage Calculator
Project Category Innovation
Abstract Warfarin is widely used around the world for the prevention and treatment of thrombosis and venothromboembolism. Consequently, anticoagulation is monitored by measurement of the international normalized ratio (INR), and warfarin dose is adjusted to maintain the INR within a target range, between 2 and 3 for most patients. Despite its efficacy, warfarin has many shortcomings. One of the drawbacks of warfarin use is the complexity of its dosing. This is due to the ability of warfarin to interact with many commonly use drugs, herbs, lifestyle changes and foods, which subsequently will augment or lessen its anticoagulation effects. This makes it harder for healthcare providers to pinpoint the correct dose of warfarin for individual patients and increased the risk of getting bleeding and thrombosis. Calculating the precise warfarin dosage during consultations with patients is time consuming as the dosage needs to be counted weekly and must be tallied with the changes of INR. Furthermore, there is still a trend among healthcare providers in Malaysia to adjust warfarin doses based on daily dose adjustment and not weekly dose adjustment. This necessitates a need for the calculations proposed by the MTAC Warfarin Protocol to be more convenient and accessible.
Validation Status Validated
Validation Date 2019-08-08


Staff Status
Mohamad Izwan Bin Ismail, Dr Leader


Event Name Event Date Event Level Achievement Event Venue
Pharm - IIDEx 2019 2019-08-01 Campus Gold Faculty of Pharmacy, UiTM Selangor, Puncak Alam Campus